Pensar con y a partir del operón
Un análisis histórico y filosófico del razonamiento basado en casos
DOI:
https://doi.org/10.18270/rcfc.4679Palabras clave:
biología molecular, regulación genética, epistemología, sistemas complejos, estilos de razonamiento científico, instanciación, razonamiento basado en casosResumen
Este artículo sostiene que el operón lac propuesto por François Jacob y Jacques Monod en 1961 superó los campos de la cinética enzimática y la genética bacteriana en los que se estableció originalmente porque impulsó una metodología de análisis, el razonamiento basado en casos dentro de las ciencias biológicas. Analizamos dos modos de razonamiento basado en casos: pensar con y a partir del operón, y concluimos que el operón descrito en E. coli sirvió en primer lugar como punto focal para comparar diferentes casos de fenómenos similares. Más adelante, los elementos extraídos del operón lac se volvieron útiles como parte de un enfoque novedoso de organismos complejos, lo que Jacob llamó una lógica de lo viviente.
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